6月26日 Jon M. Oatley: Molecular Determinants of the Stem Cell State in the Mammalian Male Germline


报告题目:Molecular Determinants of the Stem Cell State in the Mammalian Male Germline
报告人:Jon M. Oatley, Associate Professor, School of Molecular Biosciences, College of Veterinary Medicine, Washington State University.
主持人:王媛 教授
报告时间:2017年6月26日 10:00-11:30
报告地点:闵行生科院534报告厅
主办单位:生命科学学院,科技处
 
报告人简介:
1994-1999  University of Nevada-Reno, B.S. in Animal Sciences
2001-2004  Washington State University, Ph.D. in Animal Sciences/Reproductive Biology, Mentor: Dr. Jerry J. Reeves
2011-2014  Assistant Professor, School of Molecular Biosciences, College of Veterinary Medicine, Washington State University
2014-Present  Associate Professor, School of Molecular Biosciences, College of Veterinary Medicine, Washington State University.
2013-Present  Director, Center for Reproductive Biology, Washington State University
 
报告摘要:
Dr. Oatley will discuss the key functional and molecular features are that define a stem cell in the mouse male germline, in particular our discovery of ID4 as a specific marker of spermatogonial stem cells, the generation of an Id4-eGfp transgenic reporter line, and the role that ID4 plays in maintaining the stem cell state. He will talk about how we have utilized the Id4-eGfp transgenic to develop a high throughput screen for identifying novel transcription factors that are important for maintenance of the stem cell pool.