6月28日 罗振革:Unveiling Genetic Traits for Cortex Evolution


报告题目:Unveiling Genetic Traits for Cortex Evolution
报告人:罗振革上海科技大学
主持人:殷东敏 博士
报告时间:20196281500(周五下午)
报告地点:
中北校区 脑功能基因组学研究所一楼


报告人简介:

罗振革,1988年本科毕业于南开大学生物系;1991年和1995年于军事医学科学院获得硕士学位和博士学位,随后任助理研究员、副研究员;2000年至2003年,在美国阿拉巴马大学伯明翰分校神经科学系做博士后;2003-2018年在中国科学院神经科学研究所先后任研究员、高级研究员,所长助理,副所长;201810月加入上海科技大学生命科学与技术学院,任终身正教授,副院长。奖励和荣誉称号:中科院“百人计划2003),中国青年科技奖(2007),国家自然科学基金委杰出青年基金(2008),上海市优秀学科带头人2008),国务院特殊津贴专家(2010),上海市自然科学牡丹奖(2011),张香桐青年神经科学家奖(2011),中国科学院杰出科技成就集体奖(2011),谈家桢“生命科学创新奖”(2012),上海市“领军人才”(2012),国家特殊人才支持计划(万人计划)科技创新领军人才(2018)。现任中国神经科学会理事,神经发育与再生分会会长;中国细胞生物学会理事资深理事,学术委员会成员。担任Journal of Molecular Cell Biology, Molecular Brain, Molecular and Cellular Neuroscience, Developmental Neurobiology, Neuroscience Bulletin等国内外学术期刊的编委。主要研究神经发育与再生分子细胞机制,在Nat.Cell Biol., Neuron, Dev. Cell, PNAS, eLife等期刊发表系列论文。


报告内容:

       It is generally assumed that the expansion of the mammalian neocortex during evolution correlates with the increase in intelligence, and this process involves increased production of cortical neurons, resulting from an extended neurogenic period as well as increased proliferative ability of neural stem cells and progenitors.To fit into a limited cranium, expanded cortical surfaces are folded to form gyri and sulci. Given that genetic differences between humans and other species are likely to be the causes of human-specific traits, including complexity of cortical morphology, extensive studies have been performed in comparing genes and genetic elements of different species of primates and mammals. In this speech, I will introduce our efforts and findings on identification of genetic elements that are involved in cortex expansion during evolution, with particular focus on gene duplication and novel fusion transcript.